Salicylamide is an active ingredient in BC powder. What is its purpose? Consider the directing effects of the substituents on salicylamide and predict the possible structures of the iodination products. What will be the major product? Explain.
Salicylamide has a hydroxyl group at the ortho position of benzalamide. Salicylamide has pain-relieving and antipyretic properties.
Directing Effect
The group present on a ring has a vital role in the regioselectivity of an upcoming group. Activators generally give the ortho (o-) and para (p-) product, whereas the deactivators yield meta (m-) product.